News from Buckingham Institute for Translational Medicine

As one of the UK’s most respected medical research laboratories, there is always a lot happening at the Clore Laboratory. Below is a brief selection of just some of the activity at, and acclaim for, the Clore Laboratory at the University of Buckingham.

1 October 2017
Paul Trayhurn  has taken on the role of Editor-in -Chief of the Journal of Nutritional Science – the Nutrition Society’s Open Access journal.

September 2017
Paul Trayhurn was an invited speaker at the 39th ESPEN Congress on “Clinical Nutrition & Metabolism”, held in The Hague, Netherlands, where he spoke on “Tissue Hypoxia and Energy Metabolism”, and in October he gave an invited talk on “Hypoxia and Adipose Tissue Dysfunction in Obesity” at the 21st IUNS International Congress of Nutrition in Buenos Aires, Argentina.

At the Buenos Aires Congress he also attended a meeting of the Scientific Committee (of which he is a member) organising the next FENS European Congress of Nutrition which will be held in Dublin in 2019; he also attended the IUNS General Assembly as the proxy delegate for the Norwegian Nutrition Society.

January 2017
Paul Trayhurn was an invited speaker at the Janssen-Cilag Meeting on “Clinical Conundrums in Diabetes”, held at the Royal College of Physicians, London, where he gave a talk on “Brown, Beige and White Fat: Understanding their Significance in Type 2 Diabetes”.

22 September 2016
Professor Andrew Krentz chairs the inaugural European Health Innovation Collaborative conference at Imperial College London.

May 2014
Dr Malgosia Kepczynska has joined BITM at the University of Buckingham as a Postdoctoral Research Fellow.

3 April 2014
Professor Jon Arch, Dean of the School of Science at the University of Buckingham, presented Pharmacotherapy for obesity: limited options but plenty of ideas at The 2014 Obesity Summit, a conference organised by Euroscicon in London.

25 March 2014
A commentary by Professor Cawthorne on the failure of current obesity treatments which focus on diet and exercise advice was published in the Pan European Networks Science and Technology journal. link  

17-21 March 2014
Professors Trayhurn, Arch and Cawthorne attended the International Congress on Obesity in Kuala Lumpur, Malaysia. Professor Trayhurn was chairman of the International Scientific Committee for the Congress.

19 March 2014
Professor Jon Arch, Dean of the School of Science at the University of Buckingham, presented Pharmacotherapy – The Options at the 12th International Congress on Obesity in Kuala Lumpur, Malaysia.

25 March 2014
A commentary by Professor Cawthorne on the failure of current obesity treatments which focus on diet and exercise advice was published in the Pan European Networks Science and Technology journal. link  

5 March 2014
Maysson Ibrahim
 presented her paper on ‘Rational Identification of Prognostic Markers of Breast Cancer’ in an oral presentation at the Bioinformatics 2014 conference in Angers, France.

3 March 2014
Osman S Osman presented a poster entitled ‘Automated Analysis of Collagen Histology in Ageing Skin’ at the Bioimaging 2014 conference in Angers, France.

Maysson Ibrahim chaired a session today at the Bioinformatics 2014 conference in Angers, France.

December 2013
Malgosia Kepczynska completed her PhD and successfully passed her PhD viva.

Her PhD thesis was entitled ’’The impact of maternal over-nutrition and maternal obesity on the development of obesity in the offspring’’.

29 July 2013
We welcomed two new clinical MSc students in the lab today, Dr Adil Amin and Dr Hasham Kayani.  We hope they enjoy their time and research in Buckingham.

19 June 2013
Parvathy Harikumar’s first manuscript entitled ‘Collagen Remodelling and Peripheral Immune Cell Recruitment Characterises the Cutaneous Langerhans Cell Histiocytosis (LCH) Microenvironment’ has been accepted for publication in the International Journal of Dermatology. Well done Parvathy! abstract

15 May 2013
5 bioimaging posters were presented at Biotrinity 2013.

Taban Majeed presented a poster entitled ‘Breast Border Extraction and Pectoral Muscle Removal in Medical Lateral Oblique Mammogram Images’.

Dr Joanne Selway presented a poster entitled ‘A Novel Unsupervised Multi-resolution Approach for Efficient Histological Analysis of Whole Slide’.

Osman S Osman presented a poster entitled ‘A Novel Method for Automated Analysis of Skin Histopathology’.

Shan Khazender presented a poster entitled ‘A Study in Enhancing Static Ultrasound Images for Classification of Types of Ovarian Tumours’.

Maysson Al-Haj Ibrahim presented a poster entitled ‘A Pathway Enrichment and Gene Network Analysis Method for Biomarker Identification’.

14 May 2013
Professor Paul Trayhurn presented a talk entitled ‘Brown Adipose Tissue – from the Past to the Present’ at ECO2013, Liverpool, UK.

Professor Jon Arch chaired the BPS sponsored session ‘Recent Advances in the Search for Anti-obesity Drugs’ at ECO2013, Liverpool, UK.

12 May 2013
Dr Claire Stocker presented a poster at the ECO2013 conference in Liverpool, UK entitled ‘Expression of the n-3 Fatty Acid Receptor Sensor GPR120 in Mouse Adipose Tissue’.

Dr Joanne Selway presented a poster at the ECO2013 conference in Liverpool, UK, entitled ‘A Novel Automated Image Analysis Method for Accurately Quantifying Adipocyte Size’.

11 May 2013
Professor Mike Phillpott, Centre for Cutaneous Research, Barts and The London School of Medicine and Dentistry gave an oral presentation on the collaborative work between his lab and the Clore Laboratory on PTCH1 signalling through non-canonical pathways. The abstract for this work can be found at: Journal of Investigative Dermatology  2013, 133(S1) S68, 332. link

9 May 2013
Dr Kenneth Langlands presented a poster at the IID2013 conference in Edinburgh, UK, entitled ‘A Novel Automated Image Analysis Method for Rapidly Segmenting and Quantifying Cutaneous Features: Identification of Genotypes with Clinical Features’.  It was also published in Journal of Investigative Dermatology, 2013, 133(S1) S142, 838. link

Dr Joanne Selway presented a poster at the IID2013 conference in Edinburgh, UK, entitled ‘Transcriptional Profiling Demonstrates Novel Therapeutic Targets in Langerhans Cell Histiocytosis’, also published in Journal of Investigative Dermatology, 2013, 133(S1) S139, 818. link

Parvathy Harikumar presented a poster at the IID2013 conference in Edinburgh, UK, entitled ‘A Comparative Study of Langerhans Cell Histiocytosis (LCH) and Non-melanoma Skin Cancer Transcriptional Profiles’, also published in Journal of Investigative Dermatology, 2013, 133(S1) S69, 407. link

19 April 2013
The full text version of Osman S Osman’s publication entitled ‘A Novel Automated Image Analysis Method for Accurate Adipocyte Quantification’ is now available here. link

10 April 2013
The journal Adipocyte has accepted Osman S Osman’s first publication entitled ‘A Novel Automated Image Analysis Method for Accurate Adipocyte Quantification’. Well done Osman.

14 June 2012
POSTER PRESENTATION  at the Association of Studies on Obesity (ASO) meeting
‘’Plasma adipokines are altered during pregnancy in mouse dams fed a high fat diet’’ Kępczyńska,’’Healthy beginning-preventing obesity from infancy’’, Leeds Metropolitan University, UK.
Presented by PhD student Malgosia Kepczynska in London, UK

3 June 2010
Clore Laboratory staff publish research on the roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids

5 May 2010
Clore Laboratory experts join biochemists from Australia and Texas to publish research on Chemerin, a novel adipokine in the regulation of angiogenesis in the Journal of Clinical Endocrinology and Metabolism

9 April 2010
Dr Mike Cawthorne co-authors article on Taspoglutide, an analog of human glucagon-like Peptide-1 with enhanced stability and in vivo potency, published in Endocrinology

18 October 2009
Clore Laboratory poster at World Diabetes congress in Montreal

17 October 2009
Clore Laboratory postgraduate student wins first prize for poster presentation at Polish obesity congress

17 October 2009 
POSTER PRESENTATION at the II Congress of the Polish Association for the Study of Obesity (PASO)
’’Obesity from childhood to adulthood’’, The Castle of the Pomeranian Dukes in Szczecin, Poland.
Presented by PhD student Malgosia Kepczynska in Szczecin, Poland.

1 October 2009
Clore Laboratory acquires Aperio imaging system for determining pancreatic islet cell mass

28 September 2009
Avijit Guha Roy awarded first Monique Heald Scholarship in Clore Laboratory

14 September 2009
Claire Stocker edits new type 2 diabetes text book

2 September 2009
Professor Paul Trayhurn joins Clore Laboratory

30 August 2009
Nuffield Science Bursary students complete projects in the Clore Laboratory

18 August 2009
Clore Laboratory wins grant from Danish agency for Science, Technology and Innovation

5 August 2009
Dr Valur Emilsson rejoins Clore Laboratory as Honorary Fellow in Bioinformatics

13 July 2009
Dr Claire Stocker invited to Rank Prize Symposium

24 June 2009
John Rumberger awarded Doctor of Philosophy by the University of Buckingham

19 June 2009
ORAL PRESENTATION at the 2nd INTERNATIONAL BRUSSELS PANCREATIC ISLET SYMPOSIUM
’’Maternal fat feeding during both the periconceptual and gestational period in the mouse: effects on the later health of her offspring’’ given by PhD student Malgosia Kepczynska in Brussels, Belgium

16 June 2009
Strategic alliance with GW Pharmaceuticals on cannabinoids for metabolic disease

24 April 2009
Avijit Guha Roy awarded degree of Master of Science in Bioinformatics by the University of Buckingham

6 March 2009
Nobel Laureate Sir Martin Evans gives seminar in Clore Laboratory

26 February 2009
Patent application on use of insulin sensitisers in senile dementia and memory loss receives notice of allowance

3 February 2009
Mike Cawthorne discusses diabetes drug development at industry meeting

23 January 2009
Mike Cawthorne proposes radical rethink of diabetes treatment

22 January 2009
Jon Arch lectures to diabetes specialists on anti-obesity drugs

7 January 2009
Professors Arch and Cawthorne to speak at National Diabetes Conference

20 November 2008
Scholarship fund established in memory of Monique Heald

21 October 2008
Plant derived PPAR activators described in Journal of Nutritional Biochemistry paper

17 October 2008
HRH The Duke of Kent visits the Clore Laboratory

15 October 2008
Clore Laboratory research highlighted in British Journal of Pharmacology commentary

6 October 2008
Professor Emran Chowdhury joins Clore Laboratory as a Commonwealth Fellow

25 September 2008
Jon Arch gives lecture on drug discovery strategies at SMR meeting

24 September 2008
Jon Arch lectures at Metabolic Diseases meeting

26 August 2008
Article on programming effect of leptin published in Trends in Biotechnology

15 August 2008
Clore Laboratory Contract Research portfolio expanded

24 July 2008
Jon Arch talk on β3-adrenoceptor agonists for Hans Zaagsma symposium published as review

17 July 2008
Atypical β-adrenoceptor pharmacology described in BJP paper

8 July 2008
Malgosia Kepczynska awarded MSc for research on preprodynorphin gene

23 June 2008
Metabolic studies on cannabinoids presented at ICRS 2008

2 June 2008
Research outsourcing opportunities in diabetes and obesity

17 May 2008
Review presentation on metabolic programming at ECO2008 congress

7 May 2008
Diabetes and Obesity Outsourcing Opportunities

10 April 2008
Lectures by Jon Arch and Mike Cawthorne presented at IBC conference on Targeting Metabolic Disorders

9 January 2008
Jon Arch article on novel anti-obesity drugs and satisfying the regulators

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